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March 1, 2024

Ruth Scherz-Shouval, PhD

Weizmann Institute of Science

ICRF Project Grant

For tumors to expand, metastasize, and evade immune surveillance, cancer cells must recruit normal, non-cancerous cells that provide a suitable local “neighborhood” for cancer-cell proliferation. This can cause inflammation at the site of the tumor, which may lead to aggressive disease. In patients with inflammatory bowel disease, chronic inflammation of the colon may increase the risk of developing colitis-associated colon cancer. Dr. Scherz-Shouval is researching ways to block the pro-tumorigenic factors activated by colitis.

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