Gali Prag, PhD

Proteins that stimulate cell division must be tightly regulated to prevent excessive division which can lead to cancer, but it is nearly impossible to inhibit the activity of these proteins, termed “undruggable” by the pharmaceutical industry. The ubiquitin system regulates the levels or activities of many proteins in human cells. Using a novel molecular search engine, the Prag lab is studying drugs that can recruit the ubiquitin system to cause degradation of those proteins that promote development of cancer.

View Grant Recipient Profile