Yael Mardor, PhD

ICRF is currently supporting nine projects in the area of breast cancer research. Meet one of the newly-funded researchers for 2021-2022 below:

Yael Mardor, PhD, a recipient of an ICRF Acceleration Grant at Chaim Sheba Medical Center, is researching breast cancer that has metastasized to the brain. Herceptin® is a drug that specifically targets breast cancer cells that carry high levels of the HER-2 protein. It can control breast cancer that has metastasized anywhere in the body except the brain, where the blood brain barrier (or BBB) inhibits access. The Mardor team has pioneered a safe and non-invasive approach for disrupting the BBB with short, repeated electrical field treatments, and will use this method to develop a platform that causes transient disruption of the BBB to permit efficient delivery of Herceptin® to the brain.

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