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February 1, 2024

Noga Ron-Harel, PhD

Technion, Israel Institute of Technology

The Marjorie B. Cohen Memorial Research Career Development Award

Aged cancer patients are less tolerant to the detrimental side effects of classical therapies, especially immunotherapy, as the immune response may weaken with age. Dr. Ron-Harel is investigating cellular and systemic effects of aging on immunotherapy, looking at T cells’ central role in the immune defense against cancer. Her team hopes to identify metabolic barriers impairing T-cell therapy in the aged, which could lead to the development of novel treatments that improve therapeutic outcomes by enhancing the metabolic fitness of aged T cells.

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