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April 29, 2022

Efrat Shema, PhD

Weizmann Institute of Science

ICRF Research Career Development Award Recipient

May is Brain Cancer Awareness Month

ICRF is currently supporting several projects in this area of cancer treatment. Meet one of the currently funded researchers below:

Genes are packaged by proteins called histones, which regulate gene activity, and studies have shown that many gliomas carry mutations in genes that encode histones. Efrat Shema, PhD, the recipient of an ICRF Research Career Development Award (or RCDA) at the Weizmann Institute of Science, is trying to identify new drug targets and improve future treatments for glioma patients. To achieve this goal, she has recently developed a novel, single-molecule technology to study changes in the modifications of histones and related proteins that regulate gene expression, and will use it to study mutations in both pediatric and adult gliomas. Her analyses should yield new data on genome regulation in cancer, and open the way to new therapeutic opportunities for glioma patients.

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