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March 30, 2023

Avram Hershko, MD, PhD

Technion, Israel Institute of Technology

ICRF Research Professorship Grant Recipient

During the process of cell replication, abnormalities can occur. One such abnormality is when identical sets of chromosomes do not replicate equally into the new cells; some cells have too many chromosomes while others have too few. This inequality is key for the development of tumors: too many growth-stimulating genes in a cell can lead to uncontrolled growth, and too few inhibitors of growth in a cell can also cause uncontrolled growth. The goal of Dr. Hershko’s research is to identify how they might therapeutically inhibit the development of these abnormal cells.

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