Avram Hershko, MD, PhD

During the process of cell replication, abnormalities can occur. One such abnormality is when identical sets of chromosomes do not replicate equally into the new cells; some cells have too many chromosomes while others have too few. This inequality is key for the development of tumors: too many growth-stimulating genes in a cell can lead to uncontrolled growth, and too few inhibitors of growth in a cell can also cause uncontrolled growth. The goal of Dr. Hershko’s research is to identify how they might therapeutically inhibit the development of these abnormal cells.

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