Neta Erez, PhD

Tel Aviv University

Neta Erez, PhD PhD

Tel Aviv University

Neta Erez, PhD
Sackler Faculty of Medicine
Tel Aviv University
ICRF Project Grant Recipient

Prof. Neta Erez is the Head of the Laboratory of Tumor Biology and Chair of the Department of Pathology in the Sackler School of Medicine at Tel Aviv University. She has been involved in cancer research from the earliest stages of her research career, and has been funded continuously by ICRF since 2011.

The Erez team is studying cancer-related inflammation and the role of stromal and immune cells in supporting the metastasis of breast cancer tumor cells to the lungs. Cancer mortality is almost exclusively a result of tumor metastasis. Nevertheless, very little is currently known about the role of the metastatic microenvironment in allowing disseminated tumor cells from the primary tumor to propagate and colonize the metastatic organ. Therefore, she feels that elucidating the pathways and discovering target molecules in the metastatic stroma should be of great clinical importance.

Prof. Erez’s goal is to understand how cells in the microenvironment of tumors — in particular, fibroblasts and immune cells — facilitate the growth of metastatic tumor cells. To date, most anti-cancer therapy is applied following operative resection of the primary tumor, in order to prevent disease relapse; thus, making the microenvironment at the metastatic organ an important target for therapy. Moving forward, she hopes to discover molecular pathways that would lead to the development of novel therapies to efficiently inhibit the development of breast cancer metastases.

Prof. Erez lives in Nes-Ziona, Israel, with her husband, Dr. Robert Hoffman. She has a 14 year old son and an 11 year old daughter.

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